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Houston, TX (Sports Network) - Jeremy Guthrie and Michael Cuddyer both made their Rockies debut and Eric Young scored the go-ahead run in the top of the eighth inning Friday as Colorado defeated the Houston Astros, 5-3, in the season opener for both teams.

Guthrie (1-0), who spent the previous five seasons with the Baltimore Orioles and made three Opening Day starts in that span, allowed three runs on four hits and three walks in seven innings.

Cuddyer spent his first 11 years with the Twins before signing with Colorado during the offseason and went 2-for-4 with a run batted in.

Troy Tulowitzki smacked a solo homer and Rafael Betancourt picked up the save with a scoreless ninth.

Carlos Lee and Brian Bogusevic hit back-to-back solo home runs in the fourth inning for Houston, which lost 106 games last season. The Astros committed four errors in their sixth consecutive Opening Day loss.

Starter Wandy Rodriguez gave up three runs -- none earned -- on six hits and two walks in 6 1/3 innings. Fernando Rodriguez (0-1) allowed the go-ahead run in the top of the eighth to take the loss.

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