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MINNEAPOLIS - Kennys Vargas homered for the second consecutive night and Eduardo Nunez had four hits as the Minnesota Twins defeated the Chicago White Sox 11-4 on Wednesday.

The Twins broke loose for five runs in the fifth inning to break a 3-all tie and set up Trevor May (1-4) for his first major league win. Vargas' RBI single and Eduardo Escobar's two-run triple did the bulk of the damage for Minnesota.

Vargas added a two-run homer deep into the second deck in left field in the sixth. Since being called up from the minors on Aug. 1, Vargas has 31 RBIs — third-most in the majors during that span.

May allowed three runs and six hits while striking out six in five innings.

The Twins jumped out to a 3-0 lead in the first behind Nunez's RBI triple and back-to-back doubles from Josmil Pinto and Oswaldo Arcia.

White Sox starter John Danks (9-10) settled down to hold the Twins scoreless for the next three innings, and Chicago got back into it. Dayan Viciedo's two-run homer into the second deck in left brought the White Sox within a run, and Adam Eaton's RBI single tied it in the fifth.

The game was halted in the bottom half by a 16-minute rain delay. When play resumed, Vargas lined Danks' first pitch into right field for an RBI single to give the Twins a 4-3 lead.

Four batters later, Escobar hit reliever Matt Lindstrom's first pitch into the right-field corner for a two-run triple.

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